Comparative analysis between dermoid and epidermoid cyst
DOI:
https://doi.org/10.5281/zenodo.7888482Keywords:
Dermoid Cyst, Epidermoid Cyst, Congenital AnomaliesAbstract
Introduction: epidermoid and dermoid cysts are benign lesions that often simulate a brain tumor, both clinically and imaging-wise.
Objective: to comparatively characterize dermoid and epidermoid cysts.
Method: a narrative review of the available literature was carried out using the synthetic and historical-logical analytical methods through articles retrieved from databases such as PubMed, Scopus, Scielo, Google Scholar, performed on epidermoid cysts during the months of June-July 2022. A total of 24 reference articles addressing the main clinical-epidemiological characteristics of the disease in question were selected.
Development: epidermoid cysts arise from epithelial cells retained at the time of neural tube closure and can also occur after trauma. This type of cysts lack sebaceous glands and hair follicles, they are filled with epithelial cells, keratin, water and cholesterol, unlike dermoid cysts. The proximity to the cranial nerves adds to the semiology characteristics of their lesion by compression, especially at the base of the skull.
Conclusions: epidermoid cysts are pearly lesions, congenital and in some cases acquired, they lack hair follicles and sebaceous glands, unlike dermoid cysts. The age of debut of dermoid cysts is usually in childhood, while for epidermoid cysts it is 40 to 50 years. The clinical manifestations of dermoid and epidermoid cysts depend on their location. The recommended treatment for this type of cysts is total surgical resection if possible.
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References
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22. Aboud E, Abolfoth M, Pravdennkova S, Gokoglu A, Gokden M, Al-Mefty O. Giant intracranial epidermoids: is total removal feasible? [Internet]. The j neuros. 2015 [citado 19/07/2022]. Disponible en: https://thejns.org/view/journals/j-neurosurg/122/4/article-p743.xml
23. Balasundaram P, Garg A, Prabhakar A, Devarajan L, Gaikwad S, Khana G. Evolution of epidermoid cyst into dermoid cyst: Embryological explanation and radiological-pathological correlation. Neuroradiol J. [Internet]. 2019 [citado 19/07/2022]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410456/
24. Miller M, Chahlavi A. Intradural intramedullary dermoid cyst in a 42-year-old man at the L1-L2 region. North American Spine Society Journal [Internet]. 2022 [citado 19/07/2022];10:100124. Disponible en: https://www.sciencedirect.com/science/article/pii/S2666548422000270
2. Fuster Cristian, Ferreira Mario, Condomi Alcorta Santiago, Mormandi Rubén, Cervio Andrés, Salvat Jorge. Quistes dermoides y epidermoides intracraneales. Rev. argent. neurocir. [Internet]. 2017 Sep [citado 01/03/2023] ; 21(3). Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1850-15322007000300006&lng=es.
3. Vista de Quiste Epidermoide Intradiploico con Invasión Intracerebral: Reporte de Caso y Revisión de la Literatura [Internet]. Com.ar. [citado 01/03/2023]. Disponible en: https://www.ranc.com.ar/index.php/revista/article/view/227/368
4. Zambrano Lizcano DA, Reyes Graterol EO, Chacín González JP, Pérez Velásquez BV, Stock F, Petrosino Tepedino P, et al. Quiste epidermoide intradiploico parietal izquierdo. A propósito de un caso y revisión de la literatura. 2018 [citado 01/03/2023]; Disponible en: http://bdigital2.ula.ve:8080/xmlui/handle/654321/2501
5. Téllez Isla R, Mosquera Betancourt G, Betharte Sotomayor Y, Rodríguez Acevedo AN, Guerrero Rodríguez MA. Quiste epidermoide intraventricular. Presentación de un caso. Gac médica espirituana [Internet]. 2021 [citado 01/03/2023]; 23(3):142–54. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1608-89212021000300142&lng=es
6. Ostrosky A, Luberti R, Mareso E, Klurfan Federico J. Presentación de un caso de quiste dermoide con ubicación poco frecuente. Rev Esp Cirug Oral y Maxilofac [Internet]. 2005 [citado 01/03/2023] ; 27( 1 ): 37-42. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-05582005000100006&lng=es.
7. Rappoport Wurgaft D, Rau Moreno M. Quiste dermoide latero cervical. Rev Cirugia [Internet]. 2020 [citado 01/03/2023]; 72(5):472–5. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S2452-45492020000500472&lng=es
8. Pereira RG, Ribeiro BN de F, Hollanda RT de L, Almeida LB de, Simeão TB, Marchiori E. Non-neoplastic intracranial cystic lesions: not everything is an arachnoid cyst. Radiologia Brasileira [Internet]. 2021 [citado 01/03/2023]; 54(1):49–55. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7863714/
9. Ramírez García LK, Ortiz Ramos DL, Gómez Cabrera CG, Vigoa Aranguren L, Rojas Rondón I, Abreu Perdomo FA. Quiste dermoide en la cola de la ceja. Rev Cuba Oftalmol [Internet]. 2014 [citado 01/03/2023];27(1):168–74. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762014000100018&lng=es
10. Zenonos GA, Fernandes Cabral DT, Olexa J, Friedlander RM. Left Sylvian fissure epidermoid cyst presenting with progressive aphasia. World Neurosurg [Internet]. 2018 [citado 01/03/2023]; 120:363–7. Disponible en: https://www.sciencedirect.com/science/article/pii/S1878875018319478
11. Vaz-Guimaraes F, Koutourousiou M, de Almeida JR, Tyler-Kabara EC, Fernandez-Miranda JC, Wang EW, et al. Endoscopic endonasal surgery for epidermoid and dermoid cysts: a 10-year experience. J Neurosurg [Internet]. 2018 [citado 01/03/2023];130(2):1–11. Disponible en: https://thejns.org/view/journals/j-neurosurg/130/2/article-p368.xml
12. de Macêdo Filho LJM, Aguiar GCM, Pessoa FC, Diógenes GS, Borges FS, Joaquim AF, et al. Intraparenchymal epidermoid cyst close to Broca area-awake craniotomy and gross total resection. World Neurosurg [Internet]. 2020 [citado 01/03/2023]; 141:367–72. Disponible en: https://www.sciencedirect.com/science/article/pii/S1878875020313930
13. Schiff D, Wen PY. Uncommon brain tumors. Neurol Clin [Internet]. 1995 [citado 01/03/2023]; 13(4):953–74. Disponible en:: https://www.sciencedirect.com/science/article/pii/S0733861918300276
14. ClinicalKey [Internet]. Clinicalkey.es. [citado 01/03/2023]. Disponible en: https://www.clinicalkey.es/#!/content/book/3-s2.0-B9788491138334000676?scrollTo=%23hl0001276
15. Jamjoom D, Alamer A, Tampieri D. Correlation of radiological features of white epidermoid cysts with histopathological findings. Sci Rep [Internet]. 2022 [citado 01/03/2023]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831518/
16. Yasargil M, Abernathey C, Sarioglu A. Microneurosurgical treatment of intracranial dermoid and epidermoid tumors [Internet]. Neurosurgery [Internet]. 1989 [citado 01/03/2023]. Disponible en: https://journals.lww.com/neurosurgery/pages/default.aspx
17. Altschuler E, Jungreis C, Sekhar L, Jannetta P, Sheptak P. Operative treatment of intracranial epidermoid cysts and cholesterol granulomas: report of 21 cases. Neurosurgery [Internet]. 1990 [citado 19/07/2022]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/2330082
18. Fatterpekar G, Naidich TP, Som PM. The teaching files: Brain and spine. Philadelphia, PA: Elsevier - Health Sciences Division; 2011.
19. Hirsch B, Vaezi A. Cholesterol Granuloma and Congenital Epidermoid Tumors of the Temporal Bone [Internet]. ScienceDirect. 2008 [citado 19/07/2022]. Disponible en: https://www.sciencedirect.com/science/article/pii/B9781416024453501308
20. Mohyeldin A, Prevedello D. Epidermoid, Dermoid, and Neurenteric Cysts. Youmans and Winn Neurological Surgery 8th [Internet]. Elsevier; 2019 [citado 19/07/2022]. Disponible en: https://www.clinicalkey.es/#!/content/book/3-s2.0-B9780323661928001774
21. Nottmeier E, Sonntag V, Ames C. Spinal Cord Tumors, Treatment of [Internet]. Encyclopedia of the Neurological Sciences [Internet]. 2003 [citado 19/07/2022]; 2003:362-368. Disponible en: https://www.sciencedirect.com/science/article/pii/B0122268709006365?via%3Dihub
22. Aboud E, Abolfoth M, Pravdennkova S, Gokoglu A, Gokden M, Al-Mefty O. Giant intracranial epidermoids: is total removal feasible? [Internet]. The j neuros. 2015 [citado 19/07/2022]. Disponible en: https://thejns.org/view/journals/j-neurosurg/122/4/article-p743.xml
23. Balasundaram P, Garg A, Prabhakar A, Devarajan L, Gaikwad S, Khana G. Evolution of epidermoid cyst into dermoid cyst: Embryological explanation and radiological-pathological correlation. Neuroradiol J. [Internet]. 2019 [citado 19/07/2022]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410456/
24. Miller M, Chahlavi A. Intradural intramedullary dermoid cyst in a 42-year-old man at the L1-L2 region. North American Spine Society Journal [Internet]. 2022 [citado 19/07/2022];10:100124. Disponible en: https://www.sciencedirect.com/science/article/pii/S2666548422000270
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Published
2023-04-20
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Acurio Padilla PE, Rodríguez Acurio AM, Trávez Valencia JF. Comparative analysis between dermoid and epidermoid cyst. Univ. Méd. Pinareña [Internet]. 2023 Apr. 20 [cited 2025 Apr. 24];19:e957. Available from: https://revgaleno.sld.cu/index.php/ump/article/view/957
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