Neurological manifestations in SARS-CoV-2 positive patients
Keywords:
COVID-19, SARS-CoV-2, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms.Abstract
Introduction: Coronavirus disease 2019 mainly affects the respiratory system, however, various clinical studies have shown that the coronavirus family has a certain tropism for the nervous system.
Objective: to characterize the neurological manifestations of patients older than 18 years positive for SARS-CoV-2.
Method: observational, descriptive and cross-sectional study, in patients older than 18 years positive for SARS-CoV-2, during the period from February to August 2021, belonging to the "Manuel Piti Fajardo" Polyclinic, Cruces municipality, Cienfuegos province, Cuba. The universe consisted of 68 patients, all were studied. The variables age, sex, presence of symptoms, neurological manifestations and duration of neurological manifestations were studied. Descriptive statistics were used.
Results: there was a predominance of patients between 31 and 40 years old (36,8 %), as well as those between 19 and 30 years old (27,9 %). 52,94 % of the patients were male. 11,8 % of the patients were asymptomatic. 85 % of symptomatic patients presented headache as a neurological manifestation. Headache was found to be the longest-lasting manifestation, where 16,7 % presented it for more than 14 days.
Conclusions: Among the patients infected with COVID-19, those of the male sex, under 40 years of age, were prone to present neurological manifestations. Among the neurological manifestations, headache was common, being at the same time the symptom with the longest duration.
Downloads
References
2. Azúcar López J, Cendra Asencio M, Betancourt Bethencourt JA, Llambias Peláez JJ. Enfrentamiento social y clínico-epidemiológico a la COVID-19 en la provincia Camagüey hasta el caso 48. Rev Hum Méd. [Internet]. 2021 [citado 17/06/2021]; 21(1):1-19. Disponible en: http://scielo.sld.cu/pdf/hmc/v21n1/1727-8120-hmc-21-01-1.pdf
3. García García RJ, Sánchez Domínguez MA. Crisis sintomáticas agudas y epilepsia en niños y adolescentes en época de COVID-19. Rev Cubana Pediatr [Internet]. 2020 [citado 20/07/2021]; 92(Supl. especial):e1182. Disponible en: http://revpediatria.sld.cu/index.php/ped/article/view/1182/559
4. León Castellón R, Bender del Busto J, Velázquez Pérez L. Afectación del sistema nervioso por la COVID-19. Anales de la Acad de Cienc de Cuba [Internet]. 2020 [citado 2021 Jul 19];10(2):[aprox. 0 p.]. Disponible en: Disponible en: http://www.revistaccuba.cu/index.php/revacc/article/view/760/796
5. Llaro Sánchez MK, Gamarra Villegas BE, Campos Correa KE. Características clínico-epidemiológicas y análisis de sobrevida en fallecidos por COVID-19 atendidos en establecimientos de la Red Sabogal-Callao 2020. USMP. [Internet]. 2020 [citado 2021 Jul 25]; 20(2):e1229. Disponible en: https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/1229/742
6. Ferrer Castro JE, Sánchez Hernández E, Poulout Mendoza A, del Río Caballero G, Figueredo Sánchez D. Caracterización clínica y epidemiológica de pacientes confirmados con la COVID-19 en la provincia de Santiago de Cuba. MEDISAN [Internet]. 2020 [citado 21/07/2021]; 24(3):473-485. Disponible en: http://medisan.sld.cu/index.php/san/article/view/3145/pdf
7. Arriola Torresa LF, Palomino Taypeb KR. Manifestaciones neurológicas de COVID-19: Una revisión de la literatura. Neurolog Argent [Internet]. 2020 [citado 2021 Jul 19]; 12(4): 271-274. Disponible en: https://www.elsevier.es/es-revista-neurologia-argentina-301-articulo-manifestaciones-neurologicas-covid-19-una-revision-S1853002820300689
8. Guzmán Del Giudice OE, Lucchesi Vásquez EP, Trelles De Belaúnde M, Pinedo Gonzales RH, Camere Torrealva MA, Daly A, et al. Características clínicas y epidemiológicas de 25 casos de COVID-19 atendidos en la Clínica Delgado de Lima. Rev Soc Peru Med Interna [Internet]. 2020 [citado 2021 Jul 25]; 33(1):15-24. Disponible en: http://revistamedicinainterna.net/index.php/spmi/article/view/506/561
9. Ministerio de Salud Pública. Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud 2020. [Internet] La Habana: Editorial Ciencias Médicas; 2021 [citado 31/08/2021]. Disponible en: https://temas.sld.cu/estadisticassalud/2021/08/11/anuario-estadistico-de-salud-2020/
10. Mariños Sánchez E, Espino Alvarado P, Barreto Acevedo E. Neurological manifestations associated with COVID-19 in Edgardo Rebagliati Martins Hospital, Peru. Rev Neuropsiquiatr [Internet]. 2020 [citado 2021 Jul 25]; 83(4): 243-256. Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S0034-85972020000400243&lng=es.
11. Pérez Abreu MR, Gómez Tejeda JJ, Dieguez Guach RA. Características clínico-epidemiológicas de la COVID-19. Rev Haban Cienc Méd [Internet]. 2020 [citado 20/07/2021]; 19(2):e3254. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/3254/2505
12. Guan W, Ni Z, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl [Internet]. 2020 [citado 2021 Jul 25]; 26(4): 34-57. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266766/
13. Mao L, Wang M, Chen S, He Q, Chang J, Hong C, et al. Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study. SSRN Journal [Internet]. 2020 [citado 2021 Jul 25]; 67(8):21-37. Disponible en: https://www.medrxiv.org/content/10.1101/2020.02.22.20026500v1
